Hepatitis A Vaccine

What you need to know:

1. What is hepatitis A?
Hepatitis A is a serious liver disease caused by the hepatitis A virus (H.A.V.). H.A.V. is found in the stool of persons with hepatitis A. It is usually spread by close personal contact and sometimes by eating food or drinking water containing H.A.V.

Hepatitis A can cause mild “flu-like” illness, jaundice (yellow skin or eyes), severe stomach pains and diarrhea.

People with hepatitis A often have to be hospitalized (up to about 1 person in 5).

Sometimes, people die as a result of hepatitis A (about 3 to 5 deaths per 1,000 cases).

A person who has hepatitis A can easily pass the disease to others within the same household.

Hepatitis A vaccine can prevent hepatitis A.

2. Who should get hepatitis A vaccine and when?
WHO?

Some people should be routinely vaccinated with hepatitis A vaccine:

• All children 1 year (12 through 23 months) of age.

• Persons 1 year of age and older traveling to or working in countries with high or intermediate prevalence of hepatitis A, such as those located in Central or South America, Mexico, Asia (except Japan), Africa, and eastern Europe.

• Homosexuals

• Abusers of injectible drugs.

• Persons with chronic liver disease.

• Persons who are treated with clotting factor concentrates.

• Persons who work with H.A.V.-infected primates or who work with H.A.V. in research laboratories.

Other people might get hepatitis A vaccine in special situations:

• Hepatitis A vaccine might be recommended for children or adolescents in communities where outbreaks of hepatitis A are occurring.

WHEN?

For travelers, the vaccine series should be started at least one month before traveling to provide the best protection.

For others, the hepatitis A vaccine series may be started whenever a person is at risk of infection.

Two doses of the vaccine are needed for lasting protection. These doses should be given at least 6 months apart.

3. Some people should not get hepatitis A vaccine or should wait.
• Anyone who has ever had a severe (life-threatening) allergic reaction to a previous dose of hepatitis A vaccine should not get another dose.

• Anyone who has a severe (life threatening) allergy to any vaccine component should not get the vaccine. Tell your doctor if you have any severe allergies. All hepatitis A vaccines contain alum and some hepatitis A vaccines contain 2-phenoxyethanol.

• Anyone who is moderately or severely ill at the time the shot is scheduled should probably wait until they recover.

• Tell your doctor if you are pregnant. The safety of hepatitis A vaccine for pregnant women has not been determined. But there is no evidence that it is harmful to either pregnant women or their unborn babies. The risk, if any, is thought to be very low.

4. What are the risks from hepatitis A vaccine?
The risk of hepatitis A vaccine causing serious harm, or death, is extremely small.

Getting hepatitis A vaccine is much safer than getting the disease.

Mild problems
• soreness where the shot was given (about 1 out of 2 adults, and up to 1 out of 6 children)
• headache (about 1 out of 6 adults and 1 out of 25 children)
• loss of appetite (about 1 out of 12 children)
• tiredness (about 1 out of 14 adults)

If these problems occur, they usually last 1 or 2 days.

Severe problems
• serious allergic reaction, within a few minutes to a few hours of the shot (very rare)

5. What if there is a moderate or severe reaction?
What should I look for?

• Any unusual condition, such as a high fever or behavior changes. Signs of a serious allergic reaction can include difficulty breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heart beat or dizziness.

What should I do?

• Call a doctor, or get the person to a doctor right away.

• Tell your doctor what happened, the date and time it happened, and when the vaccination was given.

6. How can I learn more?
• Ask your doctor or nurse. They can give you the vaccine package insert or suggest other sources of information.

References: Centers for Disease Control and Prevention. http://www.cdc.gov (accessed February 2008) and Committee on Immunization, Philippine Society for Microbiology & Infectious Diseases (PSMID) & the Philippine Foundation for Vaccination (PFV). Handbook on Adult Immunization for Filipinos 2004.

© 2008 L.Y.F. Vaccination & Medical Services, Inc.
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